Sentence examples for splicing suggests from inspiring English sources

Thus, our findings of alternative TPH2 splicing suggests that this intron might be important for developmental processes, as 5-HT is known to be involved even in pre-neuronal growth regulation [8], [37], [38].

Widespread co-transcriptional splicing suggests that gene expression is primarily defined by transcription time alone.

Their recurrent nature in two families and apparent lack of effect on splicing suggests that they are rare SNPs.

This unexpectedly high ratio of alternative splicing suggests that alternative splicing is important to the transcriptome diversity of T. longibrachiatum.

Furthermore, the differential expression of several RNA processing factors not involved in alternative splicing suggests that other aspects of RNA biology may play critical roles in gliomagenesis.

Our finding that methylated genes are enriched for alternative splicing suggests that, in invertebrates, exon-level DNA methylation may play a role in the construction of splice variants by positively influencing exon inclusion during transcription.

Somewhat surprisingly, several introns with weakly-structured domain V/VI helices still exhibit classical lariat splicing, suggesting that accessory factors aid in restoring a splicing-competent conformation.

Glo regulates additional RNAs, however, and mammalian homologs bind G-tract sequences to regulate alternative splicing, suggesting that Glo also recognizes G-tract RNA.

Treatment of K562 cells with RES induced a number of signature UPR markers, including transcriptional induction of GRP78 and CHOP, phosphorylation of eukaryotic initiation factor 2α (ERF2α), ER stress-specific XBP-1 splicing, suggesting the induction of UPR by RES.

Interestingly, a large number of apoptotic regulators undergo alternative splicing, suggesting that this is a crucial mechanism for survival and death decisions [24].

Here, we showed that at least two different inhibitors had the same effect on fibronectin splicing suggesting that both act via increased acetylation of histones as shared targets of different HDAC inhibitors.