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"Is she pretty?" his mother would have asked his father, wearing the same bathrobe she'd worn for weeks, her own pretty face turning spiteful.
However, in a somewhat spiteful way, while we are facing an ever increasing availability of numerous pertaining high-throughput 'omics' data including transcriptomic, proteomic and metabolomic measurements, the measurement of fluxes is still very challenging and limited to a small fraction of the reactions present in cells.
But she spoils her case by sounding spiteful.
Other than make you look petty and spiteful?
Thousands of opposition fans, faces snarled, would come together in spiteful mantra: "Yiddo!
Being spiteful, resentful, or malicious will make you look immature.
If you, as a movie star, leave your aging face like it is (what an audacious act) you can be sure that a spiteful, derogatory and sexist shit-storm will ensue that is so emotional and so full of hatred (sadly, the high majority are men) that it is very unsettling.
"I am more convinced than ever that we have a perfect storm brewing; the reforms to welfare, the economic slowdown and spiralling costs, together with an increasingly spiteful tone in how we describe people in poverty, risks the UK becoming a nation where people face destitution".
Just recently, Jesse Ewles' music video for Of Montreal's "Spiteful Intervention" hit the web and it was a strange color orgy off giant eyeballs, chromatic matter, and Kevin Barnes' face bobbing and stretching and mutating in an abyss.
He's spiteful.
"Selfish, spiteful and cynical".
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com