Sentence examples for spindle maintenance from inspiring English sources

We next tested whether Nrg1 is also continuously needed for motor coordination and muscle spindle maintenance.

However, the molecular identity of the signal(s) provided by sensory axons had not been defined, and our data indicate that Nrg1 provides a key signal for spindle maintenance.

Indeed, CDK11p58 is required for centrosome maturation, bipolar spindle assembly, maintenance of sister chromatid cohesion and cytokinesis [23], [24], [25].

Mitotic kinesins are involved in mitotic spindle assembly, maintenance and elongation, chromosome alignment and segregation, and microtubule depolymerisation, among other functions during cell division.

Downregulation and functional attenuation of Survivin revealed severe defects in mitotic spindles assembly and maintenance, compromised spindle checkpoint surveillance, aberrant chromosome movements, increase in ploidy and the inability to complete cytokinesis.

In the present study, we show that B-MYB is required not only for normal ES cell cycle progression but also for correct mitotic spindle formation and maintenance of euploidy.

In this study, we show that Bace1 controls muscle spindle ontogenesis and maintenance in the adult.

These results indicate that monastrol and STLC specifically inhibit brown algal Kinesin-5 motors that are critical for bipolar spindle assembly and maintenance.

Mud is the Drosophila counterpart of nuclear mitotic apparatus protein (NuMA), which is known to be important for spindle formation and maintenance in vertebrate cells.

Interestingly, CHEK2 also has a crucial role in the assembly of the mitotic spindle and the maintenance of chromosomal stability [ 31].

However, given that suppression is specific to sec66 ∆, it is unlikely that the role of the Sec63 complex in spindle assembly or maintenance is related to the bypass pathway of MPS2 and MPS3.