Sentence examples for spindle component from inspiring English sources

In accordance with its identification as a spindle component, Ska1 was concentrated at the outer KT in a MT-dependent manner during prometaphase, where it remained until anaphase.

PP6c and its regulatory subunits SAPS1, SAPS2 and SAPS3 were also enriched in the mitotic spindle fraction when extracts were prepared in the absence of protein phosphatase inhibitors, suggesting that either the protein phosphatase activity of PP6 is required for its association with spindles, or that phosphorylation of a spindle component is required to anchor PP6 at mitotic spindles.

The tumor in our case was also diagnosed as epithelioid type, but showed atypical findings such as solid and tubular, cystic, or spindle components in the tumor, clearly partitioned from normal liver tissue by a fibrous capsule.

Subsequently, they are assembled with the other relevant spindle components by means of the finite element method, enabling predictions as to free and forced vibration characteristics of the entire rotor system.

One of the motivations for this work was to identify novel spindle components.

Some of these proteins are known spindle components, however their direct binding to microtubules was not demonstrated before.

Most commonly, maximal activity was in Rolandic cortex, with overlapping sources for faster and slower spindle components.

The map reveals numerous interactions between spindle microtubules and the newly identified non-tubulin spindle components and highlights proteins absent from the mitotic spindle proteome.

We found that four (Mgc68500, Loc398535, Nif3l1bp1 and LSM14A) candidate spindle components clearly localized to the spindle in live cells (Figure S5B).

Because of this, numerous spindle-related studies have been realized in this system and both the methodology and tools are available for the investigation of novel spindle components.

Thus, by virtue of their localization, any newly found spindle components automatically become suspect regulators of the spindle assembly and potential targets for anti-mitotic drugs.