Sentence examples for spindle alignment from inspiring English sources

Microscopic examination revealed that worms carrying either mutant hcf-1 allele when grown at 12°C frequently display cells with multiple nuclei of heterogeneous size, extra spindle poles and improper spindle alignment; the embryos often stopped development at or prior to gastrulation (data not shown).

Cytokinesis in plants often begins with tilted spindles, indicating the absence of a spindle alignment checkpoint in plant cells.

Additionally, Orb2 mutants present with disrupted mitotic spindle alignment; results from this study suggest that it may serve to promote the localization of aPKC [ 56].

Kraut and colleagues first determined that a protein known as Inscuteable (Insc) plays an immensely important role in coordinating mitotic spindle alignment and localization of the cell-fate determinants to the basal cortex in dividing neuroblasts [ 70].

RIC8A interacts with GDP-bound G-alpha protein [ 8], has been found to be associated with mitotic spindle alignment in asymmetric cell division in the fly [ 9], and includes a protein motif that is involved in regulation of mitosis [ 10].

The PG also shows that the cell cycle is regulated by polarity-related checkpoints for septin ring organization (node 45860), spindle assembly (node 42254) and spindle alignment (node 6261).

Spindle elongation alignment was performed using a MATLAB-based script.

Mutations that affect the accuracy of spindle pole alignment and shift the plane of cell division in apical progenitors have drastic consequences for cell fate.

TGA has also proved to disturb the spindle formation, chromosome alignment and delay the extrusion of PB1 during the meiotic maturation of mouse oocytes[17].

Aurora B function is required for mitotic chromosome alignment, spindle checkpoint function, and cytokinesis.

We thus assessed the metaphase II spindle and chromosomal alignment of ovulated oocytes.