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Liver and heart ROI's were placed so as to avoid spillover from one to the other.
A morphological erosion image filtering with 4 mm size was performed over the VOI of the lung to avoid spillover contribution from the heart or liver.
To avoid spillover effects, a spherical volume-of-interest (VOI) of 2 mm diameter was drawn in the left ventricle of the heart for derivation of the IF.
The Siemens Concorde Focus 120 has a measured resolution of 1.2-1.5 1.2-1.5 35], while the VOI used for IF determmnation had a diameter of 2 mm to avoid spillover.
Considering the spatial resolution of SPECT, 15 mm was then added to the bone volume in all directions in order to avoid spillover from bone uptake into the muscle volume.
Kidney VOIs were drawn at frame 16 or 17 (5–15 min post-injection where the highest tissue-to-background contrast was observed) by tracing a segment of the cortex at the inferolateral side of the left kidney away from liver and bowel to avoid spillover, and the final VOI was defined using a 50%% threshold contour.
The cluster design is chosen to avoid spillover effects across patients of the control and intervention groups.
To avoid spillover effects within the villages, we will conduct a cluster randomised controlled trial using the village as the randomisation unit.
At the end of data acquisition, a gradient spoiler was used to avoid spillover of the protons' transverse magnetization into the next R-R interval.
In Tanzania, randomization was by facility because the DECs felt it was not "fair" to randomize by district; special attention was given to instructing the eye coordinators in the strict need to avoid "spillover" in the supervision provided.
A second set of ROIs was placed over the RV cavity in at least five transaxial planes, with ROI boundaries at least 1 cm from the RV wall to avoid spillover of myocardial activity.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com