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Advantages of cluster RCTs over individually randomised controlled trials include the ability to study interventions that cannot be directed toward selected individuals and the ability to control for "contamination" across individuals, that is, the unintentional spillover of intervention effects from one treatment group to another.
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We also randomly selected one village within 6 km of each intervention village to measure potential spillover of the interventions.
The GAR and WR were purposively sampled for rural urban balance and to avoid spillover effects during implementation of interventions, since both regions do not share a common boundary.
This is achieved by identifying the impact of intervention on physician prescribing and evaluating the level of spillover effect on future prescriptions following the intervention.
Furthermore, in relation to effectiveness, the conservative assumptions that there would be no spillover of exclusive breastfeeding into the non-intervention population, and that dropouts would have no higher than the pre-intervention exclusive breastfeeding rates, were made for all scenarios.
Local market density could also influence the size of spillover hazard and, hence, effectiveness of interventions (13 ).
Patients in a comparable neighbouring municipality (Ikast-Brande) formed the external control group which was established to control for a spillover effect of the intervention conducted within the municipality [ 29, 30].
"This points to a spillover of price pressures".
The decline fanned worries about the spillover of the West's problems into Asia.
A spillover of the mess in Syria risks ending the country's economic miracle.
Russia fears a spillover of Islamic extremism to Muslims at home.
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