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The mean spike index at baseline was 56, falling to a mean of 37 at the end of the LEV treatment period.
In addition, we calculated the complex spike index, defined as the percentage of spikes with first lag inter-spike intervals that fall between 2 and 15 msec and whose second spike is smaller than the first.
Partially randomized datasets produce long list of spanions with much reduced spike index values.
"Minor issues: Please supply the full list of spanions/spanion clusters, preferably with their spike index, as a supplementary material".
"It would be also nice to see if tiRNAs are enriched within spanions of higher spike index".
Authors' response: Only the fragments which are concentrating high spike index value spanions can pass the filtering procedure.
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Authors' response: Fig. S4 (additional file 1) presents the distribution of the spike indexes calculated from two human database sections and also suggests the preference of spanion motifs towards to the TSS segments in an indirect way.
As already shown in theory by Jung and Marron (2009), conventional PCA is strongly inconsistent as long as the strength of the underlying signal is weak, i.e. for spike indices α ≲ 0.45.
Here (mathbb{I}^{i}) is the spike train index set of neuron i.
There was a correlation between spike wave index (SWI) and language deficits in children with BCECTS, but the deficits are not dependent on age of onset, disease course, seizure frequency, spike location or seizure type.
For touch onset, each spike was indexed by the time elapsed since the closest touch onset (taking into account the latency of each cell).
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