The identified mechanisms generalize to spike generation in other cell types.
We analyzed in generic model neurons, how the temperature dependence of ionic conductances mediating spike generation can reduce the dependence of firing rate on temperature.
NMDA conductance, in general, can act more locally to lower the threshold for Ca2+ spike generation (Schiller and Schiller 2001; Polsky et al. 2004; Larkum et al. 2009).
The FHN model is a phenomenological model of spike generation, comprising of 2 variables.
Morris-Lecar model of a single neuron is used to describe the spike generation.
The cubic shape of the critical manifold provides a mechanism for spike generation and relaxation oscillations.
We present an electronic circuit modelling the spike generation process in the biological neuron.
Note that the BSG models the spike generation mechanism of the axon hillock of a biological neuron, whereas the DSP is an equivalent model of processing of the stimuli by a sophisticated neural network that proceeds the spike generation.
Therefore, stimulus processing and the spike generation mechanism are naturally separated in the neuron model considered here.
In this paper, we performed a detailed analysis of the mechanisms of spike generation and spike-adding in a transient burst.
