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Unsurprisingly, this endangered forest species is severely affected due to unmet global demands, illegal trade and harvesting, overharvesting and an epidemic mycoplasmal spike disease.
However, the havoc caused by the epidemic spike disease and the hemi-parasitic and slow-growing nature of the tree necessitated research towards the development of biotechnological means of in vitro production as early as 1963, i.e. callusing (Rangaswamy and Rao 1963).
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In India, a growing middle class with disposable income is feeding the fast food market, spiking heart disease rates and creating a diabetes population thought to be the largest in the world.
There is strong empirical evidence that evolution for enhanced microparasite virulence can proceed quickly in a culture environment because local extinction of infectious agents after spikes of disease does not occur if there is no limitation on host animals (Anderson and May 1982; Frank 1996; Ebert and Mangin 1997; Altizer et al. 2003; Murray and Peeler 2005).
While causation is still unknown, scientists studying the water problem predicted a spike in the disease.
A spike in heart disease cases may or may not follow.
Just this week, officials reported that they witnessed a spike in Legionnaires' disease – a severe form of pneumonia – after Flint began using the water from the Flint river that proved problematic.
The Cameroon Heart Foundation has noted a "sharp spike" in heart disease among its 20 million-strong population, which is served by fewer than 40 heart specialists.
In the intervening 18-month period before the state conceded Flint's drinking water was contaminated, state officials documented a spike of legionnaires' disease in the area surrounding Flint, including nine deaths, but officials haven't concluded the water source was the cause of the increase.
A number of epidemiological studies have found that deaths from heart and lung disease spike on pollution-heavy days.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com