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Data acquisition, visual stimuli, and spike analyses were performed as described (Niell and Stryker, 2008) with minor modifications.
Thus, the mass bias behavior of Cu isotopes between standard and spike analyses remained identical, and a correction on the Zn isotope ratios could be made.
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For these reasons, Ca2+ spiking analyses always require large data-sets before general trends can be clearly established.
For LFP and spike timing analyses, the alpha level was set at 0.005 to correct for multiple comparisons across time bins (10 bins of 10 ms width to span the 100 ms deflection interval).
Spike-train analyses include interspike interval distributions, Poincaré plots, event auto- and cross-correlations, spike-triggered averaging, stimulus driven and phase-related peri-event time histograms and rasters as well as frequencygrams.
Our spike-train analyses show that initial BMI operation was associated with increasing neuronal modulations, which were not merely associated with movement kinematics.
LN models and spike-triggered analyses have long been established as standard tools for analyzing responses of retinal ganglion cells.
We therefore performed spike-sorting analyses to identify putative single neuronal units from 96 channel MEA recordings in four patients with intractable focal neocortical epilepsy.
By applying systems analysis, we elucidate the mechanisms of intraciliary Ca2+ spike generation, analyse the properties of such spikes and demonstrate the conditions under which the Ca2+ surges can become repetitive.
These typically contain higher order correlations that distort the filters obtained from spike-triggered analyses, which necessitates significant correction procedures (Theunissen et al. 2001; Felsen et al. 2005; Touryan et al. 2005).
The P2X2R-dependent current spikes were analysed using the Mini Analysis Program 6.0.3 (Synaptosoft, Decatur, GA, USA).
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