Quantitative analysis showed that partial volume effects dominate spheres of volume below 11.5 mL (diameter < 28 mm), approximately.
A sphere of inclusive volume and a sphere of exclusive volume defined the binding pocket for grid-point calculation.
Moreover, extinction and absorption efficiency factors of the fractal particles are about twice as large as for the coated sphere of same volume and composition.
The starting point is the suggestion by Mathis Mathiss, 1996) to consider the ratios between the optical cross sections of randomly oriented oblate spheroids of given shape and the corresponding cross sections of the sphere of equal volume.
A NEMA IEC/2001 phantom with six fillable spheres of varying volume (0.52, 1.15, 2.57, 5.57, 11.49, and 26.52 mL) was used for the assessment of RCs (Fig. 1b d).
The phantom is provided with six fillable spheres of varying volume (0.52, 1.15, 2.57, 5.57, 11.49, and 26.52 mL), each filled with an activity concentration of 2.28 ± 0.11 MBq mL−1 at the time of acquisition.
The member particles are assumed to be spheres of a volume calculated from their user-defined hydro-dynamic radius.
Higher association of rod-shaped particles with endothelial cells was also exhibited in vivo as anti-ICAM coated rods exhibited ∼2-fold higher accumulation in target tissue (lungs) than that of spheres of identical volume.
The MCV were represented using the diameters of spheres of equivalent volume (e.g. 80 fl has a spherical diameter of 5.35 x 10 cm). Figure 4 shows the result of the simulation, normalized to eliminate effects due to particle concentration differences.
