To examine the effect of treatments on the sphere forming ability of PC cells (pancreatosphere) and disintegration of pancreatospheres, we conducted sphere disintegration assay for 10 days to generate the formation of pancreatospheres, followed by 5 days of drug treatment.
The sphere formation ability of the MRK003-treated groups was significantly inhibited in comparison to the DMSO-treated controls.
We then functionally validated the Wnt-induced differentiation by analysing the sphere forming ability of GBM cells.
We assessed the effect of TNF on the sphere-forming ability of HBL-H2B-GFP and SK-Mel28-H2B-GFP cells with the wild type and mutated BRAF V600E, respectively.
Therefore, we first investigated the effects of GLI1 knockdown on the sphere-forming ability of MDA.MB.436 cells.
Here we report, for the first time, that CDF could inactivate many functions of CSCs including self-renewal capacity as demonstrated by the inhibition of sphere-forming (pancreatospheres) ability of drug-resistant PC cells, which was consistent with inactivation of CSC biomarkers such as CD44 and EpCAM.
Games are increasingly becoming part of the fabric of formal learning, and are celebrated in this sphere for their ability to stimulate deep knowledge in compelling simulated atmospheres.
We determined the effect of EP4 antagonists or the COX-1/COX-2 indomethacindonethacin on sphere-forming ability of MDA-MB-231 cells.
But, in addition, in the Discourse on the Origin of Inequality, Rousseau argues that, with the emergence of a competitive public sphere, the ability to turn inward is increasingly compromised, because competitive relations require intense role-playing, which Rousseau calls an "excessive labor" (Rousseau 1992 [1754]: 22).
mental ability or extraordinary ability in a specific sphere of activity or knowledge.
Gifted child, any child who is naturally endowed with a high degree of general mental ability or extraordinary ability in a specific sphere of activity or knowledge.
