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In the last ten years since the concepts of Quality by Design (QbD) and Process Analytical Technology PATT) were introduced to the biotech industry, the major regulatory agencies as well as the biotech industry have spent considerable efforts to facilitate their implementation with mixed outcomes.
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And they have spent considerable effort and money trying to enroll new voters in the Independence Party, which Mr. Golisano founded, to dilute his base of support.
Ms. Barker has spent considerable effort jazzing up the lectures, which are often set in an unusual environment like a public market or an airport.
He spent considerable effort and money in a publicity campaign and won, admittedly against modest competition, as much for his determination and decency as for his anguished performance.
He has spent considerable effort attacking the union's policies in recent months and said that the lawsuit was just one of many steps he hopes will overhaul the way hiring and firing is done in the city's schools.
"We have spent considerable effort in developing the tools we will need to remove policy accommodation, and we are fully confident that at the appropriate time we will be able to do so effectively".
President Clinton's people spent considerable effort concocting a structure that would have Russia cooperating more closely with NATO on things like peacekeeping, terrorism and nuclear proliferation, but the Russians walked out in a spat over Kosovo.
Mr. Gore made his offer on a campaign day when both he and his running mate, Senator Joseph I. Lieberman, spent considerable effort rebutting one of the very advertisements that the Democrats would propose to eliminate.
Many parents will have spent considerable effort and expense to get their child into a good school – by moving house, paying for extra tuition, or attending church in order to qualify for a faith school.
Mr. Meredith, contacted by telephone, recalled that Mr. Mugabe, once a guerrilla leader, retained some of his most bitter enemies after taking power, including a head of the secret police who had spent considerable effort trying to assassinate him.
Investigators spent considerable effort trying to find the genesis of the strain in Iowa, issuing a subpoena to Iowa State University, which was known to have a sizable library of anthrax samples.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com