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At the follow-up speech examination, the presence and type of resonance problems and articulatory proficiency were determined based on patients' speech samples.
Exclusion criteria included non-verbal IQ (Columbia Mental Maturity Scale) below the 80th percentile, hearing disability, motor or structural abnormalities (Oral Motor and Speech Examination) and a co-morbid diagnosis of autism, emotional difficulties, or neurological disorders (as assessed by medical history).
For the purpose of this study, the data from the 36-month follow-up examination were considered as clinical decisions (i.e., speech therapy and/or secondary palatal surgery, or termination of routine speech examination due to normal speech-language development) made around 36 months of age or 2 years after the time of primary surgery.
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This result highlights the importance of routine follow-up speech examinations and multidisciplinary team approach for this population.
The follow-up speech examinations were administered to each participant at 12 (one month after primary palatoplasty), 15, 24, and 36 months of age.
The data on cleft type, sex, age at palatal surgery, and postoperative complications (e.g., oronasal fistula, VPI), along with secondary palatal surgery rates and the results of follow-up speech examinations, were obtained from patients' electronic medical records.
For inclusion in the current study, patients should be born with overt cleft palate, and they must have been seen for routine follow-up speech examinations at least until 36 months of age or for two years from the time of primary palatoplasty.
All subjects underwent detailed speech and language examination, neurological evaluation, neuropsychological testing and neuroimaging analysis over a span of 48 72 h.
Neurologic examination and basic speech testing have been components of the standard bulbar assessment battery for decades, yet these assessments appear to be insensitive to the early phases of bulbar deterioration.
Participants had to pass a medical examination and take a speech test to check whether they had a specific developmental speech disorder (ICD-10-Codes: F80.1, F80.2, F83).
Both groups performed equally and normally in standard audiological examinations (pure tone audiogram, speech test, and hearing-in-noise test).
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