Our impression when reading the paper was that a lot of speculative correlations are included where no biological function can be clearly associated which may be exhausting to some readers.
Although somewhat speculative, this correlation could follow from the fact that families with a highly nomadic past place more value on cutting because it potentially increases certainty about the paternity of children.
In summary, the relevance of AGD as an end point of interest in humans is entirely speculative, and the correlation reported by Swan et al. (2005) is lacking in biologic plausibility and remains unproven.
However, this correlation is speculative.
Reasons for such a correlation remain speculative, but we can at least conclude that the formation of COMP-C3b complexes does not drive activation and therefore consumption of the classical complement pathway components.
Any interpretation of this inverse correlation is necessarily speculative; however, it is plausible that it might result from shifts in the patterns of connectivity of the hippocampal network accompanying changes in network states.
The reason for the overrepresentation of positive correlations must remain speculative, however it is self-explanatory that clusters of commonly co-regulated genes or metabolites will enrich the pool of positive correlations independently of general increase or decrease.
Genotype phenotype correlations are still only speculative, due in large part to the paucity of patients with any particular mutation.
Although speculative, the following reasons might explain these correlations.
However, because the function of the P146 protein remains unknown, correlations with virulence or adhesion are speculative and need further investigation.
