According to the speculation on the function of monacolin K synthesis genes, we speculated that, mokH acts as a transcription factor, it will promoted the expression of key genes in monacolin K biosynthesis.
Increased calpain activity is a prominent feature of postmortem AD brain (Nixon, 2003), leading to speculation that NCX function may be altered during the development of AD.
The speculation that followed was intense.
Observations of these mutant phenotypes have led to the speculation that Brat may function to inhibit cell growth in one of two newly born neuroblast daughters so as to generate one neuron and one neuroblast, rather than two neuroblasts [ 32].
This leads to the speculation that both functions could be somewhat related.
At a subcellular level, the nephrocystins have been localized to a variety of sites, being found at cell cell junctions, centrosomes and primary cilia of renal epithelial cells, leading to speculation that the nephrocystins may have different functions at these various sites.
Although there are different speculations on the function of SolR [ 25], it has been confirmed that low expression of solR will enhance solvent formation [ 26].
Another speculation relates to the function of transcription factors.
The discovery that the adult human synovium contains cells that after isolation and culture-expansion display a MSC phenotype and perform MSC functions inspired the intriguing speculation that, postnatally, the synovium may function as a reservoir of stem cells for the regeneration or repair of joint tissues such as the articular cartilage, which have limited intrinsic repair potential [ 16].
Axon damage can be retrograde or anterograde damage to the nucleus, which has led to speculation that metabolism or function of nerve nuclei and central cortex may change and lose gray matter M1 volume [ 20].
