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Thus pkn2 is speculated to regulate the activity of penicillin binding proteins.
These miRNAs are speculated to regulate the expression of type I and type III collagens but also the laminin γ chain LAMC1.
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A potential regulatory element at the 5'end of the IgH locus was speculated to regulate processes such as IgH allelic exclusion, VH germline transcription, differential accessibility or usage of distal versus proximal VH gene families.
The ability of BLU to regulate transcription is speculated to influence the level of proliferation regulators, and engagement of signaling pathways involving JNK and cyclin D1 may mechanistically elucidate the tumor suppressive role played by BLU.
In contrast, the rapid and transient induction of miR-9, miR-146a and miR-155 has been speculated to negatively regulate the acute responses following activation of innate immune through down-regulation of proteins involved in the receptor-induced signalling pathways.
These promoters are very unlikely to produce a functional transcript of any sort, and we therefore speculate that its purpose is merely to regulate the expression of the transcript initiated at the upstream promoter by "blocking" the progression of the RNA polymerase II complex.
Observations suggest these epimutations have a genomic feature of CpG deserts that are speculated to have significant roles in regulating genome activity [ 22].
Therefore, we speculated that Grp58 regulates the adaptive immune response to augment cancer invasion.
Thus, it might be possible to speculate that VEGF regulates the expression of proteinase-type ADAMs.
From these data, it is tempting to speculate that E2F1 regulates the expression of genes, such as CaM-binding protein, or represses the expression of PGC-1α or PPARδ.
Therefore, we speculated that E2F1 regulated the expression of MMP-9 mediated by Sp1 or p65.
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