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Translocation of nanoparticles through the alveolar barrier, if it takes place, has been speculated to depend primarily on endocytotic-exocytotic activity and less so by paracellular transport e.g., due to histamine, hydrogen peroxide [13].
Retraction is speculated to depend largely on actin dynamics, whereas degeneration involves microtubules [ 3].
Its contribution to bacterial virulence was proven in uropathogenic E. coli[ 34] and the heme scavenging function of the hemin receptor ChuA is speculated to depend on the activity of α-hemolysin, which gains access to the intracellular heme reservoir [ 35].
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Although offshore tsunami deposits were speculated to be more common than onshore deposits (Dawson and Stewart, 2007), their actual deposition and subsequent preservation depends strongly on the local geomorpholog-ical configurations of the shelf and nearshore area and onshore conditions.
But you have to speculate to accumulate.
LM: "We must speculate to accumulate".
When business came to depend on investment, you had to weigh various possible future outcomes; when marriages ceased to be arranged, you had to speculate on the merits of potential mates.
It has depended, and continues to depend.
To depend on nothing".
In this respect, it can be speculated that depending on the epigenetic state of chromatin in the target locus, different functional domains fused to ZFs may exhibit various efficacies.
The emulsification seems to be therefore time dependent [ 11] and it has been speculated that it depends on a combination of the saccadic motion, the difference in density of intraocular fluids and silicone oil, and the gradual decrease of interfacial surface tension of the oil due to the adsorption of surface-active components from the intraocular fluids [ 3, 8, 9].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com