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Thus, we speculated that the functional role of SIRT3 in longevity and cell survival contributes to its suppression of the ROS level.
Therefore, it may be speculated that the functional effects on cell growth and motility after loss of CAR are crucially mediated by a reduced expression of α-catenin.
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We speculate that the functional biomaterial could also provide the repairing effect on extrahepatic bile duct injuries.
It is possible to speculate that the functional impact attributed to BAE could be involved in the dissociation between syndromic and functional recovery frequently observed in treatments of these disorders.
Anthropologists speculate that the functional significance of long head hair may be adornment, a by-product of secondary natural selection once other androgenic/somatic hair (body hair) had largely been lost.
In our model the same lateral interactions will be evoked during ordinary binocular viewing, which leads us to speculate that the functional significance of these asymmetric, inhibitory interactions may be importantly involved in other aspects of vision.
Hence we speculate that the functional effect of the analyzed SH2B1 variants might become detectable when a battery of different functional tests is applied.
It was tempting to speculate that the functional variation that we observed in -824T carriers could be the outcome of environmental selective pressures on alleles augmenting catecholaminergic function (Rao et al. 2007).
We speculate that the functional bias of SOPs to these categories relates to the regulation of gene expression because SOPs are located on the boundary of the regulatory elements.
From our data, it is tempting to speculate that the functional similarities between the BLA and ventral Dm may further extend to goal-directed behavior, adding new evidence for the homology of the two structures.
The authors speculate that the functional link is mediated by one of the Zn ions in the active site as well as the Ser102, a nucleophile in the hydrolysis reaction and a residue directly adjacent to D101, and that the anti-cooperativity stems from redundant effects in positioning the serine oxyanion.
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