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Thus, we speculated that in the absence of MGL, increased 2-AG concentrations mediate CB2R signaling in immune cells to modulate inflammatory responses, thereby affecting the development of atherosclerosis.
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However, we could speculate that, in the absence of EPS, the LPS layer, which is unique to gram-positive bacteria, has significantly different electrohydrodynamic properties compared to the peptidoglycan, which is the outermost layer of gram-positive bacterial cells.
Intriguingly, one may speculate that, in the absence of its physiological targets, XIST could be attracted by H3TrimK27 domains outside the Xi, modifying the epigenetic status of such regions and possibly deregulating in trans the expression of tumorigenesis related loci.
We speculate that in the absence of aPKC activity, cells that downregulate NANOG and maintain GATA6, but fail to activate GATA4, may also undergo cell death.
12 There are reasons to speculate that in the absence of scientific evidence, the prevalence of uptake of A/H1N1 vaccination in these high risk groups would remain low.
We speculate that in the absence of CCR5, MTB-specific CD4+ T cells use CXCR3 to migrate to the disease site.
This was unexpected, as we speculated that the absence of the putative negative regulator of C5aR, C5L2, should result in increased cell sensitivity to C5a.
It is speculated that the absence of a 5′ cap and 3′ poly-(A) tail limits translation initiation.
It could be speculated that in the immediate aftermath of a mass disaster, the affected children are unavoidably confronted with trauma reminders in everyday life even in the absence of a systematic exposure intervention.
In fact, it is possible to speculate that the absence of SOD1 in the loss of function mouse model omits one of the most important targets of oxidative stress in ALS that is, SOD1 itself leaving the pathogenic cascade incomplete.
One might speculate that the absence of ATGL results in intracellular TG concentrations that cannot be further increased by the additional lack of HSL.
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