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A positive spectrum score ∆ defined de-escalation.
A positive spectrum score ∆ indicated de-escalation.
Spectrum score ∆s were compared to expert review.
Hospitalization day 4 scores were subtracted from day 2 scores (i.e., spectrum score ∆).
The final spectrum score ∆ with PO credit is positive prediciting that a de-escalation event occurred.
Mean Likert scores were compared to the spectrum score ∆ credited for IV to PO conversion.
These cases were evaluated by the same experts and compared to the spectrum score ∆ as described.
The approach to assigning a numerical spectrum score to antimicrobial regimens has recently been summarized [ 7].
Limitations of the method include reliance upon VA microbiology data to define spectrum score values.
Test characteristics of the spectrum score method to predict antimicrobial de-escalation were performed as above.
Refinement and validation of the spectrum score method was performed in three stages.
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