Sentence examples for spectrum of therapy from inspiring English sources

Antimicrobial de-escalation refers to a reduction in the antimicrobial "spectrum" of therapy, through discontinuation of antimicrobials providing activity against non-pathogenic flora or changing antimicrobials to limit coverage to targeted pathogens once a patient is clinically stable [ 1- 5].

"The best results have come from a tailored mix of therapies - and theatre and the arts are a part of this complementary side of a broad spectrum of therapies.

Also the increased expression of Bmi-1 was one of the key regulatory factors determining a cellular phenotype captured by the expression of a death-from-cancer signature in a broad spectrum of therapy-resistant clinically lethal malignancies [24].

57 These exosomes increase the interferon-related DNA damage resistance signature and enhance the transcription of NOTCH target genes, thereby promoting the resistance through expanding the spectrum of therapy-resistant breast cancer cells.

A wide spectrum of therapies was prescribed in patients assigned to dual therapy and, in a greater extent, in those prescribed with 3 or more drugs.

Ongoing development of a wide spectrum of therapies for breast cancer has increased the complexity of breast cancer management in recent years.

Proposed therapeutic interventions in RP include a broad spectrum of therapies, from pharmacological treatment to surgery, reserved for complicated conditions [ 13, 14].

1, 2 The development of biologics to specifically target variable steps in carcinogenesis and metastasis have been incorporated into first- and second-line mCRC treatment strategies, broadening the spectrum of therapies for this disease.

Considering the frequency of CAM use and the wide spectrum of therapies included, it is not surprising that studies suggest that there may be important differences among CAM users, e.g. with regard to types of CAM used and how therapies are combined [ 3].

He also emphasizes careful de-escalation to a narrow spectrum of antibiotic therapy after identification of the infecting organism, and appropriate short-course therapy to limit the emergence of resistance to carbapenems.

In hospital-acquired infection, narrowing the spectrum of antibiotic therapy is usually done as de-escalation following an initially broad-spectrum therapy aimed at maximal chance for appropriate coverage.