Sentence examples for spectrum of efficacy from inspiring English sources

Atypical antipsychotics have been shown to have a wide spectrum of efficacy across multiple psychiatric diseases and to be particularly efficacious in treatment resistant cases of disorders such as schizophrenia.

Levetiracetam is an efficacious and well tolerated drug with a broad spectrum of efficacy against all seizure types and a low potential for interactions due to minimal hepatic metabolism and low plasma protein binding (<10 %) [ 108– 108].

Accordingly, a need exists to enroll recently depressed patients in maintenance studies to elucidate the complete spectrum of efficacy of putative mood stabilizers and improve the long-term treatment of bipolar depression.

A broad spectrum of efficacy; that is, not restricted to a particular seizure type or underlying cause.

Due to their broad spectrum of efficacy against common comorbidities and lack of association with abuse and dependence, serotonergic and mixed serotonergic noradrenergic antidepressants are first-line therapies for anxiety disorders.

It therefore presents a promising target for achieving potent therapeutics with a broad spectrum of efficacy and a lower rate of resistance.

52 Antibiotic misuse is the selection of antimicrobial agents with inappropriately broad spectrums of efficacy, and antibiotic overuse is an inappropriately excessive frequency or duration of antibiotic prescription.

We conclude that putative mood stabilizers must be tested in recently manic and recently depressed patients to determine their spectrum of prophylactic efficacy.

This pinnacle observation has changed a previously held notion of the linear spectrum of GPCR efficacy and uncovered a new paradigm in GPCR research and drug discovery that relies on multidimensionality of GPCR signaling.

Amongst them, two conjugates (5c and 5d) showed broad spectrum of antiproliferative efficacy on lung cancer cells with an IC50 value of 79 nM and 93 nM, respectively, whereas on colon cancer cells with an IC50 values 45 nM and 49 nM, respectively.

Accordingly, inhibitors of the renin angiotensin system have a broad spectrum of therapeutic efficacy.