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Such a profile periodicity is proved by reconstruction of the spectrum of deviation from homogeneity in every local area (see, for example, Fig. 10a and b).
The reasonableness of each pattern estimate is confirmed by similarity between the spectrum of deviation from homogeneity and its theoretical, or statistical, reconstruction for the analysed coding region.
According to the theoretical reconstructions (Fig. 5c and d) of the spectrum of deviation from homogeneity (Fig. 5b), an estimate of 66 bp appears to be more preferable.
Deviation from additivity in expression pattern of genes was commonly observed in previous studies, albeit the spectrum of deviation can be dramatically variable.
Statistical reconstruction (Fig. 7с) corresponding to the pattern size of 291 bp reconstitutes the spectrum of deviation from homogeneity (Fig. 7b), which verifies latent profile periodicity with this period.
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The histograms show more and a broader spectrum of deviations for AnxA5 (Fig. 5d) than for [18F]FDG (Fig. 5c).
These histograms more readily visualise the frequency of deviations, the groups of deviations and the breadth of the spectrum of deviations.
To maintain functional organization of a multi-cellular organism, the spectrum of deviations per cell needs to be narrower than in unicellular organisms.
Without a sufficiently strong restriction (constraints) on the spectrum of deviations, adaptive improvisation in individual cells is more disruptive to coordination between cells, tissues and organs.
Moreover, the D11 spectra of deviation from 11-profility (Fig. 6d and h) at numerous test-periods exceed the threshold (D11 > 1), indicating the absence of 11-profility in the analysed sequences.
The maximum values in the spectra of deviation from the 33-profility [Equation (3)] do not exceed a figure of one (D33 < 1) that illustrated in Fig. 3a for chicken Apo A-IV.
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