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To compare the intensities of individual specimens, we observed that the differences from the average intensity concentrate around zero and the standard deviation was only 1.09%% (Fig. 5a).
In the other specimens, we observed no significant change in the expression levels or distribution patterns.
Indeed, in breast carcinoma specimens, we observed that overexpression of MUC1-C was associated with a nuclear distribution of β-catenin in tumor tissues and increased expression of Cyclin D1 and c-Myc.
However, when we applied a polarized fluid jet to HGn39D specimens, we observed that DiASP did not label all fibers, suggesting that the unlabelled neurons did not establish synaptic contacts with hair cells of both polarities (Figure 4 E H).
Perhaps, the lower number of positive KSHV and EBV specimens we observed was a result of our including only patients whose HIV replication had been completely suppressed below the limit of plasma detectability by commercial assay for at least one year.
In the majority of specimens, we observed immature spherules, immature alone, or forming chains.
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For early explanted specimens we observe that bone ingrowth occurs primarily at the periphery of the scaffold with a constant decrease in bone mineralization into the scaffold volume.
In the XRD pattern of each specimen, we observed that diffraction peaks from the different α-NiS films were at the same phase.
Using this GAP elliptical arrangement of 55 specimens (columns), we observed a transition of gene expression patterns of 52 genes (rows) from the left side where NC clustered to the right side where AS accumulated (Fig. 3b).
Moreover, we found that mutations in BRAF and NRAS are not mutually exclusive because they were simultaneously present in the same tumor specimens and we observed that when the 2 different mutations were present one is a high-frequency mutation and the other is a low-frequency mutation.
We further performed an exploratory miRNA expression analysis of 26 paired pre- and post-chemotherapy specimens and we observed many expression changes following exposure to chemotherapy (70 miRNAs differentially expressed), which were non-overlapping with the predictive or prognostic profiles described above.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com