Sentence examples for specimens that demonstrate from inspiring English sources

For example, many centers additionally conduct testing for the BRAF V600E mutation in CRC specimens that demonstrate loss of the MLH1 and PMS2 protein staining by IHC, as presence of this mutation is strongly and negatively associated with LS.

The proportion of specimens that demonstrated CER levels above a threshold value of 10 fmole/mg protein increased sequentially from a low of 13/51 (26%) for patients less than 35 years to a high of 60/81 (74%) for patients greater than 75 years.

Surgical specimens that demonstrated none of these features were declared to be non-responders pathologically.

The fluorescence, LM and SEM images included in this article represent a subset of the experimental specimens that clearly demonstrate the observations discussed below.

Because exon 1 of VHL was covered at a lower mean depth (13×) than exons 2 (213×) and 3 (51×), the promoter region and exon 1 were separately PCR amplified and Sanger sequenced for the four specimens that did not demonstrate evidence for biallelic VHL inactivation.

Despite a bout of snow blindness, he was able to collect specimens that would ultimately demonstrate Antarctica's links to other land masses.

We retrieved cases that were thought to be unequivocal grade II PXA during the clinical evaluation of the surgical pathology specimens as well as tumors that demonstrated most of the features of PXA and were thought to be "consistent with PXA".

The development of cryo-electron microscopy (cryoEM) was a major breakthrough that demonstrated that biological specimens, including cells and "single particles," could be better preserved in vitrified water solutions, free from crystallization and staining artifacts (Dubochet et al. 1981 , 1988, in a close-to-native state.

Observed results as well as numerical simulations demonstrate that specimens that had aged longer show increased quasi-pc values.

None of the three metastases with Y373C mutations had paired primaries, although one had a paired normal bladder specimen that did not demonstrate evidence of Y373C mutation.

Instead of using pyrosequencing conventionally, to sequence a population of viruses within an individual, we interrogated a single combined pool of surveillance specimens to demonstrate that it is possible to determine TDR rates in HIV protease from a population of individuals.