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Digital PCR has been applied in quantification of EGFR mutants in clinical specimens, providing a promising molecular diagnostic tool [ 28].
This argument is supported by the study published by Irahara et al. [ 30] who compared average methylation values for LINE-1 in macrodissected colon cancers with those for matched Laser Capture Microdissection specimens providing a pure collection of tumor cells.
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Post mortem specimens provide a unique opportunity to investigate the clinical condition.
It was found that single-edge notched tension specimens provide a closely matched creep crack-tip constraint with axially cracked pipes.
While physical specimens provide a critical permanent record of biodiversity, the importance of reliable locality information collected by students and non-scientists is growing.
The amber-encased B. bruckschi specimens provide a rare 3D view of the ancient creatures' bodies.
First morning specimens provide a proxy for overnight cortisol excretion.
The high prevalence of ALDH+ cells in these three HER2-overexpression specimens provides a possibility that HER2 overexpression may drive tumorigenesis as well as ALDH expression as proposed [31].
It should be noted that out of 17 patients only 8 specimens provided a positive microbiological culture.
Association of PMEPA1 methylation with reduced expression of PMEPA1 in CaP specimens provided a rational for testing the methylation status of PMEPA1 in CaP cell lines.
PBDEs partition into body lipids, and direct measurement of bromodiphenyl ether congeners in biologic specimens provides a good marker of exposure.
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CEO of Professional Science Editing for Scientists @ prosciediting.com