Note that sample sizes are uneven across metabolic control indicators, because there were some blood specimens with problems for computing levels of HbA1C, Triglycerdies, LDL, and HDL.
However, an unknown number of persons have undocumented meningitis because of failure to present, pretreatment with antibiotics, lack of lumbar puncture, or problems with specimen transport or storage.
The cytological screening interpretation presents known problems with specimen collection, smear preparation and inter-observer reproducibility in all cytological categories [ 30, 31].
During the impact campaign on H-shaped specimens a major problem with the auxiliary bonding of the substrates to the mounting angles occurred in a number of specimens.
"They can handle being washed". The permanently preserved plants cost more than live plants, obviously, but Weyerhaeuser calculates a return on investment in less than two years for those who buy them because of all the problems with large living specimens in indoor plantings.
Since at least one gene was successfully amplified and sequenced from every specimen, it seems unlikely there were problems with DNA quality.
Problems with obtaining a specimen for analysis were reported for two (0.3%) patients.
There were potential problems with variability of specimen collection and processing, and the lack of data from community 2 necessitated a move to community 3. We investigated selected study households, which may not have been representative of the whole community.
Multiple biopsies are needed to limit problems with orientation of the specimens and artefact during processing and staining.
However, there are some practical problems with these methods in dealing with clinical specimens.
