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Second, the age of the donor specimens may not well represent the population typically undergoing ACL reconstruction.
The effect of the dynamic brace on older specimens may not accurately reflect the effect of the brace on the typical younger patient with a PCL- or PCL/PLC-deficient knee.
Current experimental evidence suggests that the mechanical properties of laboratory AM specimens may not be representative of those associated with parts, due primarily to differences in geometry/size which influence the thermal histories experienced during fabrication, and consequently, microstructural features, surface roughness, and more.
Studies suggest that while laboratory-derived drug-resistant bacterial isolates usually have substantial fitness deficits, resistant strains collected from clinical specimens may not be similarly impaired [17] [24].
As ovarian carcinomas can be very heterogeneous, such specimens may not be representative of the tumor in some cases.
Colorectal cancer surgery significantly impacts on intratumoral gene expression, suggesting archival specimens may not accurately reflect in situ marker levels.
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There is also the worry that the specimen may not be complete and a lot of work may be for nought.
Although direct strength tests, which are destructive in nature, are excellent for quality control during construction, their main shortcoming is that the tested specimen may not truly represent the concrete in the actual structure.
Concern that a single specimen may not correctly characterise an individual's hormone levels have long hampered efforts to study endogenous hormones in premenopausal women.
If ribosomal DNA copies within a specimen are more diverse than between specimens, phylogenetic analyses using one representative sequence for each sampled specimen may not accurately represent relationships by descent.
Therefore, the healthcare workers who provided a stool specimen may not have been a representative sample of HCWs and may have been biased towards those with no abdominal complaints, and therefore little C. difficile exposure.
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