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It's not every day that you come across a closet full of old, pickled brains, so I called Adam to learn more about the book and photos, the rare anatomical anomalies within the collection, and how the specimens may contribute to scientific research today.
Consequently, the observed down-regulation of MST-1 in rectal specimens may contribute to an enhanced cellular immune response in UC.
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Such thickness variation, so called 'lens effect', is well known for vitrified specimen, and may contribute to uneven particle distribution that can hamper efficient data collection.
However, differences in the type of specimens (urine or swabs) and if applicable, how the specimens were stored may contribute to these differences in prevalence [ 12].
However, these data also suggest that as the amount of total RNA starting material decreases the coefficient of similarity to the original specimen also decreases, which may contribute to inconsistencies in data interpretation.
These findings suggest that typical dense elastosis may be present only in the upper lobes in patients with IPPFE, and biopsy specimens from the lower lobes may contribute to misdiagnosis of IPF/UIP [ 7].
This mechanism has important implications on reloading of specimens where degradations in bone strength may contribute to age-related skeletal fragility and traumatic fractures.
Variability in the quality of specimens utilized for biomarker discovery and validation may contribute to this prognostic inconsistency.
Overexpression of the zinc transporter, ZIP4, compared with the surrounding normal tissue, is seen in 94% of clinical specimens of pancreatic adenocarcinoma, suggesting that it may contribute to the pathogenesis and progression of the disease (Li et al, 2007).
Finally, ectopic growth hormone expression has been shown in a majority of specimens of normal and malignant breast tissue, and this may contribute to breast cancer risk, possibly by increasing the local level of bioavailable IGF1.
Histological diagnosis of biopsy specimens cannot definitively identify adenomas with aggressive potential because sampling errors may contribute to the underestimation of tumour grade or depth of invasion.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com