The EGD specimens included multiple grasp biopsies of the distal esophagus, gastric antrum, and the duodenum.
Universal amplification has been performed on 87 TGCT specimens and 36 samples of CIS cells microdissected from single paraffin-embedded tumour sections from 40 patients, including multiple specimens of CIS and TGCT cells of varied histology microdissected from 24 individual patients.
Fungal recovery may be difficult in bronchogenic carcicoma because of non-communication of the lesion with main bronchus [ 11] and might have been improved in our study on including multiple specimens.
Future analyses using larger sample sizes, including multiple tumor specimens (synchronous and metachronous), might be helpful in confirming such chromosomal instability.
The M805 cell line was resistant to MTX when established from a patient's specimen, who received pre-operative chemotherapy, including multiple doses of MTX.
The within-patient mutation rate was calculated in 74 individuals with multiple specimens, including 51 relapses, allowing ≤10 SNPs, and using the first and last specimens if there were more than two.
To test reproducibility, we included multiple specimens for some of the species for which enough fresh material was available.
Three one-millimeter tissue cores from formalin-fixed paraffin embedded donor blocks were precisely arrayed into a new recipient paraffin block that included tumor specimens and controls, which included multiple cores of normal tissue from 10 different organs.
Quality control specimens for the study included multiple samples from three individuals who were not study subjects (QC-A, n = 34; QC-B, n = 20; QC-C, n = 15) and 76 duplicates from study subjects.
Genome-wide analysis suggested that all 43 pheochromocytoma specimens, including both malignant and benign ones, showed multiple copy number losses or gains.
