For quantitative analysis (see below), we included data only from specimens from which radiographs were obtained; however, we augmented our qualitative comparisons of style morphology by examining skeletal preparations.
An information integration system such as an ASMS can be particularly helpful for broad-scope scenarios by providing a unified view across and access to a wide range of data and specimens, including external data sources.
The CDEs include cancer registry data (demographic, epidemiology and follow-up) at the patient level, pathology data at the specimen level including data elements to elaborate TNM staging and tumor grading, along with block level annotation and genotype data [ 16].
For the All TCGA Qualified Specimen report, these metrics include data on specimens that meet the TCGA requirements of percent necrosis, percent tumor nuclei and warm ischemia time.
Histological data obtained from neck dissection specimens included the number of positive nodes and the presence or absence of ECS.
Among the 632 specimens included in the datasets, 338 were ADC (99 labeled and 239 unlabeled data) and 294 were SCC (56 labeled and 238 unlabeled data).
For further details concerning the specimens (including the morphometrical data), see [ 16, 17].
Further studies are underway to analyse the expression and function of LSD1 in a larger cohort of breast cancer specimens including patients' survival data to evaluate the prognostic relevance of LSD1 in breast carcinoma.
List of specimens included in phylogenetic analyses.
All specimens included contained >70% tumour cells.
