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Future studies should focus on improved detection and analysis of more cases to identify appropriate specimens in assessing clinical implications of MRD detection.
To determine the feasibility of a rapid method of processing mandible bone margins for intraoperative histopathologic examination and to assess the relative value of fine, coarse, and core specimens in assessing bone margins.
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Gulson (1996a) reported high variability in Pb levels measured in the same fingernails and toenails of various subjects, even after rigorous washing procedures; such lack of reproducibility suggests that nail specimens offer only limited scope in assessing exposure to Pb.
We wished to confirm our findings in clinical specimens by assessing whether high 8-hydroxyguanosine (8-OG) IHC staining, a well known marker for ROS levels [26], correlates with EGFR immunostaining.
We found evidence of mycobacterial DNA in the granulomas of 24% of sarcoidosis specimens when assessing for rpoB, 48% in the same population when assessing for 16S rRNA; in total, 60% were positive for either.
The associations between influenza and both enrollment site and number/type of specimens were assessed in bivariate and multivariate models in the whole population.
The performance of the unstitched and stitched specimens was assessed in terms of the energy per unit volume of damage created during impact testing, and the energy to failure of the impacted specimens during their three-point bending testing.
The mechanical behavior of differently processed specimens is assessed in both monotonic and cyclic tests aimed at clarification of the role played by different structural factors in the resultant mechanical properties.
The fretting fatigue resistance of shot and laser peened specimens was assessed in a series of tests involving measurements of the residual stress field, residual stress relaxation under the action of cyclic loads, the friction coefficient, surface roughness and material hardness.
Respiratory tract specimens were assessed in the local microbiology laboratories of each center.
A total of 196 colon specimens were assessed in this study, including colon tissue qPCR arrays (OriGene Technologies, Rockville, MD, USA) consisting of 143 cDNA samples and a well-characterised cohort of 53 paired normal and CRC specimens.
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