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In a previous study, gene expression profiling of a group of GBM specimens identified a cluster of about 50 named genes whose expression was inversely associated with survival [ 9].
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Further analysis of his diagnostic specimen identified an ALK rearrangement by fluorescence in situ hybridization (FISH).
Thereafter, he was referred for further evaluation, where analysis of his diagnostic specimen identified an ALK rearrangement by fluorescence in situ hybridization (FISH) using the Vysis (Abbott) LSI ALK dual colour, break apart rearrangement probe (Abbott molecular, Illinois, Figure 1).
Specimens identified as Influenza A positive by the Resplex II assay underwent additional singleplex real-time PCR assays for H1, H3, or pandemic H1N1-2009 as previously described [ 5, 9].
Previously published reports[2], in addition to our clinical laboratory's experience (unpublished data), have shown that specimens identified as nontypeable influenza A using this assay were uniformly confirmed to be the 2009 pandemic influenza A (H1N1) strain using the published CDC assay.
The most recent meta-analysis performed on 2554 samples from cancer patients and 3553 control specimens identified that although there was a significant association between lower L1 methylation and tumor versus normal DNA, no association for L1 methylation levels in the blood of control and cancer patients was found [ 74].
Agabus ramblae and A. brunneus were fully separated by AD, with no intermediate specimens, whilst the specimens identified as A. rufulus had an intermediate, overlapping shape (Additional file 10: Figure S3).
A total of 302 specimens identified as A. longirostris morphospecies were collected and studied from 76 sites in PNG (Table 1 and Figure 1).
However, MOTU richness was increased by one across the potential barcoding gap, due to sequences from specimens identified as A. novaezelandiae from New Zealand forming a distinct MOTU from other A. novaezelandiae from Tasmania.
Studies on plasma specimens have identified a number of candidate biomarkers [ 32– 32].
Pusztai and colleagues [ 78] extracted RNA from fine-needle aspiration specimens and identified a group of genes that predicted pathologic complete response to neoadjuvant chemotherapy.
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