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In total, studies report >700 episodes of PCP, span a period from 1976 to 2001, and include patient data and clinical specimens from multiple cities in several different countries.
Further studies may be needed to increase the number of BE progressor and non-progressor specimens by collecting specimens from multiple additional institutions prior to initiating a prospective Phase 4 study.
An alternative approach would have been to use surgical pathologic specimens from multiple different individuals.
7 Upon his death, autopsy specimens from multiple organs were notable for granulomas containing the same type of "protozoal" organisms.
As many clinical trials involve multiple centres, this sample stability provides the opportunity to collect specimens from multiple sites and analyse them in one central location.
Recently, McCarthy et al. published a meta-analysis of 76 studies all using the 27 K BeadChip array to identify sex-associated autosomal DMPs across specimens from multiple tissue types from adults and children [ 8].
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This experiment was repeated with tissue specimen from multiple (>6) independent donors.
Examining samples with a single technique over several days, as it is routinely used in most high burden settings identified between 6 and 10 of these patients, while an alternative approach of examining all specimens collected from multiple sites in a single day identified 14 of the children.
We show that specimens collected from multiple locations in six tumours revealed very little variation in MDR1 expression suggesting that the levels of MDR1 in these tumours do not vary greatly with location within the tumour mass.
Syncytin-1's expression in healthy brain specimens was derived from multiple encoding loci and linked to distinct immune and developmental gene profiles.
Specimens were obtained from multiple parts of the embolized and nonembolized liver segments.
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