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Furthermore, precise quantification of mutant alleles revealed a low correlation (r2 = 0.27) of histopathological estimates of tumor content and frequency of mutant alleles, thereby questioning the use of histopathology for stratification of specimens for individual analytical procedures.
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In this way, and through other consent-approved communication between family cancer clinics, 43 families with individuals in common have been merged into 21, ensuring data and specimens for each individual are only accessed once, and that the combined characteristics of the entire family structure can be analyzed by researchers.
Systematic weekly sampling will provide a control set of specimens for the individual and the cohort, allowing quantification of virus-specific attributable risk to illness.
In practice, >90% of receptor testing was conducted on biopsy material, and the remainder, on mastectomy tissue, but we did not have an indicator of specimen type for individual patients, so we could not use it to perform sensitivity analyses.
Although the CTB provided 137 RNA specimens for 71 individuals with PTC, we were able to use only 126 paired (tumour/normal) RNA specimens corresponding to 63 individuals.
Cryopreserved specimens for all individuals at four different time points were assessed (4 weeks following the last DNA immunization; 6 18 months later, immediately prior to rAd5 boosting; 4 weeks after rAd5 boosting; and 6 months following rAd5 boosting).
Multiple specimens from individual participants were pooled for analyses.
Cervical biopsy specimens were typed for individual HPV types by PCR.
A total of 2,786 fecal specimens from individual NP-AFP patients and second-collection specimens from 310 of the patients were examined for EV.
Such an analysis demonstrates that, even though small scale yielding conditions prevail at the crack tip, the FCG curves for individual specimens depend upon and can be arranged according to the plasticity level.
Although some scatter in the correction factor BV/TV relationships may confound accurate correction of modulus and yield stress for individual specimens, side-artifact correction is nonetheless essential for obtaining accurate mean estimates of modulus and yield stress for a cohort of specimens.
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