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The investigation of biological specimens for biochemical profiles is entering a new era with the application of novel technologies capable of mass analyses.
Gluteal muscle biopsy specimens for biochemical analysis of muscle metabolites were obtained at start and end of anaesthesia and 1 h and 1 day after recovery.
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Lenses obtained from intact postmortem eyes were the only specimens used for biochemical analysis.
Blood specimens were taken and the three urine specimens were submitted for biochemical analysis.
Fourteen dried specimens were selected for biochemical analyses.
Stool specimens were obtained for biochemical analysis (total faecal bile acid (FBA), lithocholic deoxycholic and cholic acids) and NDC isolation.
In a first stage, we used the Olympus® 2.5 mm forceps (standard-oval without needle; required work channel size: 2.8 mm Ø; Shinjuku, Tokyo, Japan) and in a second stage the Endoflex® 3.4 mm (jumbo-oval without needle; required work channel size: 3.7 mm Ø; Voerde, Germany) in order to obtain larger specimens, optimizing the adequacy of the specimens for functional and biochemical studies.
In prostate cancer, expression levels of EMT markers Twist and Vimentin - as assessed by immunohistochemistry in radical prostatectomy specimens - are independent predictors for biochemical recurrence as defined by a resurgence in serum prostate-specific antigen (PSA) levels following surgery [124].
An efficient study design includes provisions for further processing of the original samples, such as cryopreservation of isolated cells, purification of DNA and RNA, and preparation of specimens for cytogenetic, immunological and biochemical analyses.
The same mechanism of transmission probably occurred when laboratory worker 2 handled laboratory worker 1's blood culture specimen on the open bench for biochemical testing.
Prior to the collection of longitudinal pieces for biochemical analysis, representative transversal whole-gut specimens were taken from a region of the inflamed colon that corresponded to the segment adjacent to the gross macroscopic damage, and the specimens were fixed in 4% buffered formaldehyde.
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