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A blinded study was performed for each probe set using 25 normal bone marrow samples, 25 t(4 11), 20 t(6 11), 20 t(9 11), 18 t(11 19p13.1), and 20 t(11 19p13.3) leukemia specimens as defined by chromosome analysis.
The first reference partition consisted of the taxonomic affiliations of the corresponding specimens as defined in the GenBank flat files in the "organism" descriptor.
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Length of excision was defined as the distance from the distal or external margin to the proximal or internal margin of the excised specimen, as defined by the IFCPC nomenclature [ 13].
Comparing pre-acute and acute specimens, chlamydia cases had a significantly greater mean change in PSA between specimens than controls, and were more likely to have a large rise in PSA at the time of their acute specimen, as defined by both absolute and relative change.
Under optimized culture conditions, 72% of specimens yielded rapidly proliferating TILs as defined as at least one culture reaching ≥3×107 TILs within 4 weeks.
Ten (6%) mixed infections, as defined by the specimens containing more than 1 G or P genotype, were found, and 31 (18%) specimens remained untypeable.
These specimens represented moderate to severe OA as defined according to macroscopic criteria.
No lung specimens had a "not UIP pattern" as defined by the IPF consensus criteria (i.e., presence of hyaline membranes, organizing pneumonia, granulomas, marked interstitial inflammatory cell infiltrate away from honeycombing, or predominant airway-centered changes) [ 5].
Only adult specimens were used in this study, as defined by the eruption of all permanent teeth (often showing some wear), the complete ossification of the basiosphenoid suture, and the development of the sagittal crest.
Our previous study showed OCT4 and SOX2 were overexpressed in 136 HCC specimens and related with aggressive behavior as defined by large tumor size, vascular invasion, and poor survival in patients who underwent partial hepatectomy [12].
The OECD 313 experiments were performed using one test specimen from this batch, but mainly using test specimens of 5 × 2.5 × 1.5 cm3 as defined in EN 113 [26] that were vacuum-impregnated with the same preservative.
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