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Over 50 years, since 1963, the IBMP researchers apply systemic and innovational approaches to fundamental and exploratory studies in the fields of medical sciences, radiation biology, engineering science, biotechnology, etc. with participation of various biological specimens and human volunteers.
Real-time reverse transcription PCR (RT-PCR) was used to screen JEV in mosquito pools, pig serum specimens, and human cerebrospinal fluid as described (9 ).
In the present study, we first demonstrated the expression of the MUC1 antigen on human pancreatic cancer specimens and human pancreatic cancer cell lines using MAb C595.
The angles α and β were 30.4±4.1 and 9.2±1.9 degrees for male volunteers and 28.5±3.7 and 7.7±1.8 degrees for female volunteers, significant difference in these angles between cadaveric specimens and human volunteers.
The study protocol involving the use of clinical specimens and human data has been approved by the ethics committees of the Bayrische Landesärztekammer (no. 06043) and the University of Munich (no. 437 12).
Human EV-76 was detected in isolates in 1 rectal swab and 2 CSF specimens, and human EV-89 was detected in 2 rectal swabs by using amplification of VP1/2A or VP1 regions.
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Because of the impracticality/impossibility of measuring these altered radiation fields inside critical internal body organs of biological test specimens and humans, computational methods rather than direct measurements must be used.
We quantified the immunohistochemical staining for RND3 in 15 human GBM specimens and 15 human normal brain tissues, and found a significant reduction of RND3 expression in the GBM specimens compared to the normal brains (Fig. 1B).
Complete gene sequences of the nucleoprotein gene were obtained from 52 RABV-positive specimens: brain specimens from 42 dogs, brain specimens from 3 persons who died, 1 specimen from a cow that died, 5 human saliva specimens, and 1 human CSF specimen.
To determine the prevalence of AKT E17K mutations in melanoma, the most aggressive form of skin cancer, we analysed 137 human melanoma specimens and 65 human melanoma cell lines for the previously described activating mutation of AKT1, and for analogous mutations in AKT2 and AKT3.
Six cadaveric specimens and six human subjects were tested with simulated and voluntary rotation respectively.
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