Furthermore, molecular data were used for sub-classification of tissue specimens with regard to Gleason score, age and total serum PSA of the patient at RP.
With the same combination of genes we correctly sub-classified 84% of tumour specimens with regard of patient's age, 71% with regard to final RP Gleason score and 42% with regard to PSA before RP (Table 2).
In Table 2 it is also shown that the combination of 7 genes (H3, GAS1, H3, SSAT, CLU, AdoMetDC, OAZ, ODC) correctly classified 84% of cancer specimens with regard to age of the patient, 71% with regard to RP Gleason score and 42% with regard to PSA.
Only few studies have analysed the protein levels of uPA system components in RCC specimens with regard to their dependence on clinicopathological parameters and to their impact on prognosis of RCC patients.
Because this and other biobanks generally adopted TCGA standards for using key data as a proxy for specimen quality with regard to relative quality of the specimens for genomic and transcriptomic experimentation, these standards are shown within the Overview.
30 It is therefore important that the suitability of the specimen stabilization method with regard to the desired diagnostic testing be established prior to implementation.
blinded to the origin of the specimens with special regard to liver architecture, cellular changes, extent of necrosis (% of liver), and level of hemorrhage scored on a four-point scale (0 3; 0 none, 1 mild, 2 moderate, 3 severe).
Mechanical properties of specimens were characterized with regard of compressive, splitting tensile, and flexural strengths.
The specimens were evaluated with regard to synovial hypertrophy/infiltration of leukocytes and cartilage/subchondral bone erosion.
Limitations of our study include the lack of clinical data in the cadaveric specimens, in particular with regard to previous LCL lesions.
