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Since Pileou's Evenness Index and Simpson's Diversity Index are likely influenced by the very large number of unique clones in each specimen, we also compared the relative abundance of the ten most abundant T cell clones for each lesion between pairs.
Since this is not the smallest distance from the specimen, we also do not expect this to provide highest photo-thermal energy.
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With the sheet specimens we also investigated the contribution of annular collagen to the shear modulus by applying a tensile prestrain (0, 5 or 10percentt) perpendicular to the direction of applied shear stress.
We sequenced 1,141 epigean Australian specimens; we also sequenced 112 specimens from adjacent geographical areas (New Guinea, Fiji, New Zealand and New Caledonia) to cover species with wider geographical ranges than continental Australia and to include the few species of otherwise strictly Australian genera that are endemic to neighboring islands.
For a small number of specimens we also performed viral cultures and often found evidence for infectious virions (unpublished data).
Moreover, analyzing human bone marrow CLL specimens, we also observed an association of CD49d expression and high leukemic BM infiltration [ 86].
For a small number of specimens we also performed viral cultures and often found evidence for infectious virions but did not quantify them (unpublished data).
Grade information is not available in other sarcoma specimens We also investigated the status of p-Stat3 in sarcoma cell lines.
For a subsample of specimens, we also obtained partial sequences of two additional mtDNA markers: the NADH dehydrogenase subunit 2 (ND2, 1160 bp) and 5 (ND5, 1132 bp) (Additional file 1: Table S2).
In order to set up conditions to study signaling pathways in post resection specimens, we also explored the effects of pre-analytical procedures on protein status, examining tyrosine phosphorylation or expression in Western blotting experiments and time course conditions.
In line with these data, in our analysis of breast cancer specimens, we also found a statistically significant correlation (P = 0.0002) between low FBXW7/hCDC4-α expression and p53 mutation.
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