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Logistics of specimen transportation laboratory processing and result reporting must also be addressed [26].
This was demonstrated during the WYD outbreak, where the greatest delay was due to specimen transportation to the laboratory.
However, this is reliant on the PCR result being available immediately, a situation rarely achievable in clinical practice when factors such as specimen transportation and laboratory processing are taken into account.
Specimen transportation, culture methods, and species identification have been described (14 ).
All products recommend drying following sample application, which can take several hours and may delay specimen transportation and ultimately diagnostic results.
Culture for gonorrhoea has historically been problematic in clinical areas outside of hospitals because of the reduced sensitivity associated with delays in specimen transportation to the laboratory.
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It has not yet been tested on specimens preserved in alcohol, which would further simplify specimens' transportation and logistics, but very importantly this technique has high sensitivity with smear-negative specimens.
At the initial baseline visit, two cervical samples were taken; the first, for conventional cytology, was taken with an extended-tip spatula, the second sample was taken using a cone-shaped cervical sampler brush (Qiagen, Hilden, Germany), which was placed into specimen transport medium for transportation to one of two laboratories.
An additional factor that could have compromised the results is the highly decentralized source of the specimens, and the transportation of specimens to a centralized laboratory may not have been optimal for the recovery of influenza viruses from nasopharyngeal swabs.
Numerous factors including temperature, packaging, courier, sample type, import/export requirements, seasons, costs and transit time/ship days can affect biological specimen integrity during transportation domestically and internationally.
For human papillomavirus (HPV) DNA detection, specimen collection and transportation using a dry swab without transport medium has advantages, in various situations, over liquid media.
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