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We could examine, by studying multistage individually microdissected tumor components from the same specimen, the extent of heterogeneity associated with chromosome 18p LOH (Fig. 2).
For each lung specimen, the extent and intensity of positive staining were graded on a scale of 0 4+ by two blinded observers on two separate occasions using coded slides as previously described (Sano et al. 1992).
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In all of the specimens examined, the extent of redistribution of Am and Pu was higher in the fuel of O/M ratio of 1.98 than in that of 1.95.
On the other hand, the addition of clay significantly reduces the thermal expansion in both the flow (FD) and transverse directions (TD) of injection molded specimens; however, the extent of reduction of CTE in the FD is much greater than in the TD.
GLUT-1 and CA IX were expressed in all specimens, but the extent of this expression varied considerably.
At a minimum, the feasibility of each procedure will depend on budget, transport, availability, health of the source-specimen, and the extent of degradation prior to or after sample collection.
In addition to specimen mass change, the extent of internal oxidation and the depletion of β phase in the substrate were evaluated.
Load/energy-time curves and load-displacement curves were extracted from the experimental data, and non-destructive C-scanning was performed on all pre- and post-impacted specimens to quantify the extent of damage incurred.
An ex vivo study of human coronary artery plaque specimens showed that the extent of inflammation at the plaque shoulders appears to correlate with degree of vulnerability slightly unstable plaques have little or no inflammation at the plaque shoulders, while highly unstable plaques have extensive inflammation at the plaque shoulders [10].
The other source of uncertainty in the measurements was the correlation of the measurement position on the specimen to the microscopic extent of the pathology in the tissue.
Given the extent of specimen handling required, specimen conservation practices are integral.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com