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This result is coherent with the IR spectrum obtained in this specimen that exhibited an intense and well-resolved amide I band.
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Notably, amongst specimens that were cultured using "in-house" plasma, 4 of the 5 specimens that exhibited the poorest TIL growth in vitro (M30, 33, 39, 43; see Figure 1A, B) also showed a paucity of CD3+ T cells by IHC compared with specimens that exhibited efficient TIL growth (Figure 2).
Among 44 specimens that exhibited aneuploidy, 41 specimens (93.2%) showed p53-positive staining and high BubR1 expression (P < 0.01; Table 2).
In order to confirm our findings, we repeated the immunohistochemistry from serial sections in all tumour specimens that exhibited EGFR-negative and p-EGFR-positive staining and the obtained results were identical.
In addition, recent studies have successfully identified cells within lung cancer specimens that exhibit stem-like properties.
Finally, the fatigue strength of the additively manufactured specimens was compared with that exhibited by vacuum melted specimens of the same steel reported in literature.
From these assays, 15 specimens yielded at least one TIL culture that exhibited tumor reactivity in vitro.
Zou et al. investigated Maspin expression in 97 prostate tumor specimens showing that tumor cells that exhibit histological response to neoadjuvant "hormonal treatment" showed Maspin expression.
One specimen that has never been exhibited is Willi the Dimetrodon — a Permian-era mammalian ancestor that resembles a giant lizard with a spiny fin — which was found by the museum's team on a dig in Baylor County.
The percentage of viable tumor cells of the entire specimen that exhibit PD-L1 plasma membrane staining at any intensity was recorded as the PD-L1 tumor score (Fig. 1, bottom).
Results of testing demonstrated that RPC specimens that included MF exhibited 8 58% higher load carrying capacity compared to the reference NF specimens.
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