Test choice will determine the kind of specimen required to conduct the test.
The amount of specimen required in conventional XRD has limited its application, but where synchrotron XRD is available, much smaller specimens can be successfully examined [15].
Each bone specimen required approximately 4 hours for data acquisition.
*Bacteria contamination; specimen required filtering.
†Mold contamination; specimen required filtering.
The growing deluge of data from next-generation sequencers leads to analyses lasting hundreds or thousands of compute hours per specimen, requiring massive computing clusters or cloud infrastructure.
As such, it is crucial for TB vaccine researchers to "cast a wide net" when assessing immune responses to clinical trial candidates while minimizing the amount of specimen required to generate these data.
Other examples of specimen requiring amplification for genome-wide characterization of gene expression include purified populations of cells obtained by either flow cytometry, laser capture microdissection, breast ductal or bronchial lavage, or microendoscopy.
Where there were substantial delays in this step (> 50 days from sample date to genotype production, n = 27), this was usually due to the specimen requiring more than one attempt to amplify.
