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Test choice will determine the kind of specimen required to conduct the test.
As such, it is crucial for TB vaccine researchers to "cast a wide net" when assessing immune responses to clinical trial candidates while minimizing the amount of specimen required to generate these data.
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Several aspects were studied with the numerical model: the effect of the used virtual fields, the minimum number of specimens required to identify the parameters, the stress distribution obtained from the specimen and its influence in the identification performance.
The numbers of specimens required to obtain representative values for quantitative analyses were selected according to Stach et al. (1982).
Power analysis was also performed to provide an estimate of the number of specimens required to detect a 10% change of the DTI indices in each white matter structure.
The minimum number of specimens required to produce a reliable estimate has been discussed (e.g., Biggin et al. (2003); Paterson et al. (2010)), see also Suttie et al. (2011).
The specimens required to confirm a provisional diagnosis of bluetongue in a live animal are coagulated blood and non-coagulated blood in heparin.
The specimens required to confirm a provisional diagnosis of mucosal disease in cattle are coagulated blood, blood in heparin and samples of lymph nodes and spleen.
The specimens required to confirm a suspected case of FMD are samples of fresh vesicle fluid and epithelium fragments from ruptured and unruptured vesicles.
The specimens required to confirm a provisional diagnosis of PPR are newly dead carcasses as well as blood in ethylenediamine tetra-acetic acid (EDTA) or heparin and samples of lymph nodes, tonsils and red lung consolidation from animals killed early in the course of the illness.
The critical difference (reference change value, RCV) for significant changes in serial results (P less than 0.05) and the number of specimens required to estimate the homeostatic set-point of an individual (within ±10% with a confidence of 95%) will also be estimated.
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