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Further analysis of his diagnostic specimen identified an ALK rearrangement by fluorescence in situ hybridization (FISH).
Thereafter, he was referred for further evaluation, where analysis of his diagnostic specimen identified an ALK rearrangement by fluorescence in situ hybridization (FISH) using the Vysis (Abbott) LSI ALK dual colour, break apart rearrangement probe (Abbott molecular, Illinois, Figure 1).
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In a previous study, gene expression profiling of a group of GBM specimens identified a cluster of about 50 named genes whose expression was inversely associated with survival [ 9].
The specimen identified by Myers is an adult pterosaur of the toothless variety and while larger than most birds, wasn't among the largest pterosaurs, Myers said, noting it had a wing span between 12 and 13 feet or 3.6 to meters.
We extracted DNA from a specimen identified as P. haustrum (FMNH 223530) from the Rio Ucayali in Peru, above its confluence with the Río Marañón.
Almost all identified amphipods belonged to a single species, Themisto gaudichaudii; the only exception was a single specimen identified as Hyperia macrocephala.
In one specimen we identified a novel HTN3-MSANTD3 gene fusion, and in another a novel PRB3-ZNF217 gene fusion.
Studies on plasma specimens have identified a number of candidate biomarkers [ 32– 32].
Pusztai and colleagues [ 78] extracted RNA from fine-needle aspiration specimens and identified a group of genes that predicted pathologic complete response to neoadjuvant chemotherapy.
Recently, Andersen et al (2012) reported transcriptome analyses of 104 cholangiocarcinoma specimens and identified a poor prognostic subgroup characterised by KRAS mutations, and activation of EGFR and HER2 signalling pathways.
Gene expression studies performed on human breast cancer specimens have identified a breast cancer molecular subtype 'claudin-low' population [ 68] that expresses an overlapping gene signature with that of CSC populations enriched with CD44+/CD24-/low CD44+/CD24-/loworescells-activated cell sorting (FACS), and mammospheres [ 69].
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