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To assess whether use of a single voided specimen for classification of proteinuria was sufficiently representative, we estimated the rate of persistent proteinuria in patients with micro- or macroalbuminuria and at least one additional albumin excretion measurement during the time window of this cohort.
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WLG evaluated tumour specimens for staging classification and tumour content.
The assembled genome sequence of an individual will also be only one representation of the total variation present in a species (paralleling the use of 'type specimens' for taxonomic classification).
For specimen classification we used the Nearest Neighbour (NN) classifier, a statistical multi-factorial analysis tool known to perform well specifically for cancer classification when compared with other methods.
All specimens used as examples for classification in the next paragraphs were prepared in this way.
Only molecular data were used for classification of specimens.
Specimens lacking sufficient epithelial cells for classification were categorized as ICMD (insufficient cells to make a diagnosis).
Stringency level I was used in all contexts except for classification of tissue specimens into CIMP and CIMP categories where stringency level II provided a better distinction (Fig. 2).
In 1917 patients with reference pathologist assessment of both diagnostic biopsy and resected specimen, the classification was different for 75 (4%) patients.
Two-layer Al Mn alloy specimens with four kinds of defects are used for classification.
All specimens were re-evaluated for diagnosis following the criteria for classification of lung cancer by the World Health Organization (WHO) [ 10], and 133 squamous cell carcinomas and 146 adenocarcinomas were confirmed.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com