A blinded study was performed for each probe set using 25 normal bone marrow samples, 25 t(4 11), 20 t(6 11), 20 t(9 11), 18 t(11 19p13.1), and 20 t(11 19p13.3) leukemia specimens as defined by chromosome analysis.
The first reference partition consisted of the taxonomic affiliations of the corresponding specimens as defined in the GenBank flat files in the "organism" descriptor.
Under optimized culture conditions, 72% of specimens yielded rapidly proliferating TILs as defined as at least one culture reaching ≥3×107 TILs within 4 weeks.
When discussing molecular features of one specimen, the set of SES-characters as defined here should also be provided for clear communication.
The OECD 313 experiments were performed using one test specimen from this batch, but mainly using test specimens of 5 × 2.5 × 1.5 cm3 as defined in EN 113 [26] that were vacuum-impregnated with the same preservative.
These specimens represented moderate to severe OA as defined according to macroscopic criteria.
Ten (6%) mixed infections, as defined by the specimens containing more than 1 G or P genotype, were found, and 31 (18%) specimens remained untypeable.
No lung specimens had a "not UIP pattern" as defined by the IPF consensus criteria (i.e., presence of hyaline membranes, organizing pneumonia, granulomas, marked interstitial inflammatory cell infiltrate away from honeycombing, or predominant airway-centered changes) [ 5].
Only adult specimens were used in this study, as defined by the eruption of all permanent teeth (often showing some wear), the complete ossification of the basiosphenoid suture, and the development of the sagittal crest.
